Polynucleotides (PN)

What are polynucleotides?

Polynucleotides are bio-stimulating injectable treatments derived from highly purified DNA fragments. These DNA fragments are sourced from fish (salmon) DNA, which is processed and refined to remove proteins and impurities, making it suitable for medical and aesthetic use.

The structure of polynucleotides allows them to support skin repair processes, improve skin quality, and enhance tissue resilience over time.

How they work…

PN treatments support cellular repair mechanisms, improve skin quality, and help strengthen the skin barrier. They are particularly suited to delicate areas such as the under-eye region.

How treatment is administered…

Polynucleotides are administered via superficial injections into targeted areas. Treatments are usually delivered as a course.

Expected Outcomes

  • Improved skin texture

  • Enhanced elasticity

  • Reduction in crepiness or skin thinning

  • Improvements develop progressively over time.

Longevity

Results typically last 4–6 months, with maintenance treatments advised.

Risks and Possible Side Effects

  • Mild swelling or redness

  • Temporary bruising

  • Injection site discomfort

Important information

Polynucleotide treatments are derived from purified fish (salmon) DNA. While these products are highly refined and allergy reactions are rare, they may not be suitable for individuals with known fish allergies. In addition, patients with dietary, ethical, or lifestyle preferences that preclude the use of animal-derived products should inform us during consultation. Alternative treatment options can be discussed where appropriate.

Combination Skin Boosters with Polynucleotides

What is this treatment?

Combination skin boosters containing hyaluronic acid and polynucleotides combine hydration with regenerative skin support. The polynucleotide component is derived from purified fish (salmon) DNA, while the hyaluronic acid component supports hydration and skin elasticity.

This combination aims to improve overall skin quality while supporting repair and regeneration.

How they work…

These products aim to hydrate the skin while simultaneously supporting tissue repair and collagen stimulation.

How treatment is administered…

Administered via micro-injection techniques, typically as part of a treatment course.

Expected Outcomes

  • Enhanced hydration

  • Improved skin quality

  • Increased skin resilience

Longevity

Results typically last 4–6 months, depending on individual response and treatment protocol.

Risks and Possible Side Effects

  • Redness

  • Swelling

  • Mild bruising

Important for new patients

All new patients interested in any treatments must first book a consultation appointment.

A face-to-face consultation and treatment planning is required before treatment can be provided. Please do not book a treatment appointment if you are a new patient. Treatment appointments are reserved for patients who have already attended a consultation and have an agreed treatment plan. Any treatment appointment booked by a new patient may be declined and changed to a consultation appointment.